I have several patients asking about intermittent fasting and looking for articles. Do you have any research that you can point to for patients looking for guidance and is this actually a good idea? I have patients looking to fast for 12-14, (which really seems like it should just be categorized as a way to get away from  cultural tendency towards unnecessary night time binge eating which makes sense) but also the extreme of going nearly 24 hours several times per week. This seems like a disruption to the normal digestive process? I can see that the MMC cleans out the system and has a specific and regular place but could too much lead to paresis or disregulation? Any thoughts you have on the subject would be very appreciated!